Thursday September 1, 2016 |
14:15 | Registration |
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15:00 | Welcome and opening |
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15:00 | Session Chair |
Prof. Koen AUGUSTYNS (UNIVERSITY OF ANTWERP, Antwerp, Belgium) |
15:05 | Case Histories of Fragment-Based Drug Discovery. |
Dr David REES (ASTEX PHARMACEUTICALS, Cambridge, United Kingdom) |
15:35 | Heterocycles and Medicinal Chemistry: the Importance of Innovative Synthesis |
Dr Anthony WOOD (PFIZER, Stevenage, Herts, SG1 2NY, United Kingdom) |
| YMCS Competition Presentation Session I |
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16:05 | New Avenues in Protein Labeling - Exploiting Dna for Directing Chemical Reactions
Winner of the young medicinal chemist meeting in Denmark (CP01) |
Dr Anne Louise Bank KODAL (NOVO NORDISK, Bagsværd, Denmark) |
16:25 | Drug Design, Synthesis and Biological Evaluation of Antiretroviral and Anticancer Agents
Winner of the young medicinal chemist meeting in Italy (CP02) |
Dr Valeria FAMILGLINI (UNIVERSITY OF ROME, Rome, Italy) |
16:45 | Development of Potent, Cell-Active Inhibitors of the
Mycobacterium Tuberculosis Cholesterol Oxidase
Cyp125 (OC01) |
Ms Madeline KAVANAGH (UNIVERSITY OF CAMBRIDGE, Cambridge, United Kingdom) |
17:05 | Flash Poster Presentations |
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| FP01- Toward Libraries of Artificial Macrocycles
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Mrs Eman ABD ELRAHEEM (GRONINGEN UNIVERSITY, Groningen, The Netherlands) |
| FP02 - Discovery, Structural Exploration and Biological Profiling of a Novel Class of Antimycobacterial Dpre1 Inhibitors
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Ms Olga BALABON (UNIVERSITY OF ANTWERP, Wilrijk, Belgium) |
| FP03 - Orally Bioavailable Antimalarial 4(1h)-Quinolone Prodrugs with Single-Dose Cures
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Dr Fabian BROCKMEYER (NORTHEASTERN UNIVERSITY, Germany) |
| FP04 - Developement of Synthesis Methodology for Dna-Encoded Small Molecule Screening Libraries
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Dr Mateja KLIKA SKOPIC (TECHNISCHE UNIVERSITÄT DORTMUND, Dortmund, Germany) |
| FP05 - Fishing for an Off-Target": Deconvoluting the Molecular Mechanism of Gpcr-Induced Macrophage Chemotaxis"
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Dr Maria CHATZOPOULOU (UNIVERSITY OF OXFORD, Oxford, United Kingdom) |
| FP06 - Design, Synthesis and Pharmacological Evaluation of Fluorescent Tools for Studying Cannabinoid Type 2 Receptor
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Ms Anna COOPER (UNIVERSITY OF OTAGO, Dunedin, New Zealand) |
| FP07 - Development of Novel, Selective and Irreversible Pi3kδ Inhibitors
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Mr Sam DALTON (UNIVERSITY OF STRATHCLYDE, Glasgow, United Kingdom) |
| FP08 - Identification of Novel Non-Natural Supramolecular Ligands as Stabilizers of 14-3-3? Protein-Protein Interactions
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Dr Alba GIGANTE (DUISBURG ESSEN UNIVERSITY, Tres Cantos-Madrid, Spain) |
| FP09 - Targets in Orphan Diseases and Their Repurposing Candidates - Analysis with a Knime Workflow Using Open Phacts
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Ms Jana GURINOVA (UNIVERSITY OF VIENNA, Vienna, Austria) |
| FP10 - Selectivity Profiling of the Human Monoamine Transporters: A Case Study on Cathinone Analogs
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Ms Eva HELLSBERG (UNIVERSITY OF VIENNA, Vienna, Austria) |
| FP11 - Photoswitchable 4-(Piperidin-4-Yl)-1-Hydroxypyrazole Analogues for the Gaba Type A Receptors
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Ms Henriette KIHL (UNIVERSITY OF COPENHAGEN, Copenhagen, Denmark) |
| FP12 - Extending Sar of Bile Acids as Fxr/Tgr5 Modulators: Synthesis and Biological Activity of Ring C Modified Cdca Derivatives |
Ms Serena MOSTARDA (UNIVERSITÀ DEGLI STUDI DI PERUGIA, Perugia, Italy) |
| FP13 - Lead Optimisation of a Novel Class of Trypanosomacidal Agents
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Ms Harriet NEWSON (UNIVERSITY OF WESTERN AUSTRALIA, Australia) |
| FP14 - Synthesis and Biological Evaluation of Diaromatic Guanidinium-Like Derivatives as Protein Kinase Inhibitors for the Treatment of Cancer
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Ms Viola PREVITALI (TRINITY COLLEGE DUBLIN, Dublin, Ireland) |
| FP15 - Development of Novel 1,4-Benzodiazepines as Antitrypanosomal Agents
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Dr Santo PREVITI (UNIVERSITY OF MESSINA, Messina, Italy) |
| FP16 - Determining the Binding Mode of 3-(1-Alkyl-1h-Imidazol-5-Yl)-1h-Indoles
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Dr Adam HOGENDORF (MAJ INSTITUTE OF PHARMACOLOGY, POLISH ACADEMY OF SCIENCES, Krakow, Poland) |
| FP17 - Targeting the Human Dihydroorotate Dehydrogenase (Hdhodh) by a Scaffold Hopping Bioisosteric Approach Using Hydroxylated Pentaatomic Heterocycles |
Dr Stefano SAINAS (UNIVERSITY OF TORINO, Torino, Italy) |
| FP18 - Towards the Elucidation of the Mechanism of Action of Small Molecule Upregulators of Utrophin Using Chemical Proteomics
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Dr Aini VUORINEN (UNIVERSITY OF OXFORD, Oxford, United Kingdom) |
| FP19 - Development of an Albumin-Binding Ligand for Prolonging the Plasma Half-Life of Peptide Therapeutics
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Mr Alessandro ZORZI (ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE , Lausanne, Switzerland) |
| FP20 - Near-Infrared (Nir) Photothermal Therapy Using Biocompatible Palladium Nanoparticles
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Dr Belen RUBIO RUIZ (UNIVERSITY OF EDINBURGH, Edinburgh, United Kingdom) |
17:45 | YMCS Poster presentation session & Networking drink |
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19:00 | End of the day |
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Friday September 2, 2016 |
| YMCS Competition Presentation Session II |
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08:30 | Antimalarial Drug Discovery: Exploring the Mep Pathway
Winner of the young medicinal chemist meeting in the United Kingdom (CP03) |
Ms Kathryn PRICE (UNIVERSITY OF LIVERPOOL, Liverpool, United Kingdom) |
08:50 | Drugging the Undrugguble: Targeting Challenging E3 Ligases
Winner of the young medicinal chemist meeting in Spain (CP04) |
Dr Carles GALDEANO (UNIVERSITAT DE BARCELONA, Barcelona, Spain) |
09:10 | Development of Highly Selective and Reversible Diacylglycerol Lipase Inhibitors
Winner of the young medicinal chemist meeting in The Netherlands (CP05) |
Dr Freek JANSSEN (LEIDEN UNIVERSITY, Nijmegen, The Netherlands) |
09:30 | Functional Lipidomics-Based Lead Discovery Reveals Novel Role of Phospholipids in Vitamin A Signaling
Winner of the young medicinal chemist meeting in Germany (CP06) |
Dr Andreas KOEBERLE (UNIVERSITY OF JENA, Jena, Germany) |
09:50 | Design, Synthesis and Biological Evaluation of Selective CDK Inhibitors based on Flavopiridol Structure
Winner of the young medicinal chemist meeting in Greece (CP07) |
Dr Nikitia MEXIA (UNIVERSITY OF ATHENS, Leeds, United Kingdom) |
10:10 | Coffee break |
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| YMCS Competition Presentation Session III |
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10:35 | Design and Synthesis of 2,2'-Diindolylmethanes to Selectively Target Certain G-Quadruplex Dna Structures
Winner of the young medicinal chemist meeting in Sweden (CP08) |
Dr Madeleine LIVENDAHL (UMEA UNIVERSITY, Umeå, Sweden) |
10:55 | Stable, Effective, and Selective Anticancer Phenolato Titanium(Iv) Complexes
Winner of the young medicinal chemist meeting in Israel (CP09) |
Dr Sigalit MEKER (THE HEBREW UNIVERSITY OF JERUSALEM, Kfar Yona, Israel) |
11:15 | Glyco-Conjugated Photosensitizers: From Synthesis to Validation in Cancer Photodynamic Therapy
Winner of the young medicinal chemist meeting in Portugal (CP10) |
Ms Patricia PEREIRA (UNIVERSIDADE DE AVEIRO, Aveiro, Portugal) |
11:35 | Discovery of Cct251921: A Potent, Selective and Orally Bioavailable Small Molecule Modulator of the
Mediator Complex-Associated Kinases Cdk8 and Cdk19 (OC02) |
Dr Aurelie MALLINGER (INSTITUTE OF CANCER RESEARCH, London, United Kingdom) |
11:55 | Lunch |
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| YMCS Competition Presentation Session IV |
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13:15 | How to Design Cell Permeable Non-Peptidic Macrocycles (OC03) |
Dr Björn OVER (MACROCYCLE ADME, BEYOND RO5 AND NATURAL PRODUCT-FRAGMENTS, Landvetter, Sweden) |
13:35 | New 3d-Scaffolds for Fragment-Based Lead Discovery (Fbld): Exploration of Chemical Space Using Functionalized Spirohydantoins
Winner of the young medicinal chemist meeting in France (CP11) |
Mr Hugues PREVET (LABORATORY U1177 - UNIVERSITY OF LILLE, Lille, France) |
13:55 | Discovery Of Novel Atpase Inhibitors Of Dna Gyrase And Topoisomerase Iv Starting From Marine Sponge Alkaloid Oroidin
Winner of the young medicinal chemist meeting in Slovenia (CP12) |
Prof. Tihomir TOMASIC (UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
14:15 | Purine Mimicking 3'-Ethynylribofuranose Nucleosides: New Opportunities for an Old Sugar Modification
Winner of the young medicinal chemist meeting in Belgium (KVCV) (CP13) |
Dr Fabian HULPIA (UGENT, Beerse, Belgium) |
14:35 | Experimental Platform for Characterization and High-Throughput Screening of Acetylcholinesterase Inhibitors
Winner of the young medicinal chemist meeting in Poland (CP14) |
Dr Piotr DRACZKOWSKI (UNIVERSITY OF LUBLIN, Lublin, Poland) |
14:55 | Novel Derivatives of the Tspo Ligand Dpa-714 For in Vivo Pet Imaging of Neuroinflammation (OC04) |
Mrs Fanny CACHEUX (CEA, Orsay, France) |
15:15 | Voting Break |
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15:30 | Closing and award ceremony |
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