Registration

Opening Ceremony

Opening Lecture
Synthetic and Medicinal Chemistry for Biologics (IL01)

Welcome Reception

Registration

Session Chair

Innovation in Synthetic Fluorine Chemistry through Use of Flow (IL02)

MicroCycle: A Machine Learning Driven, Automated and Integrated Platform for Drug Discovery (IL03)

Divergent Synthesis as an Emergent Tool for Drug Discovery (OC01)

Coffee-break and Exhibition

Synthesis of Fluorinated Molecules Using Modern Synthetic Tools (IL04)

Chemical Probes and their Relevance for Drug Discovery Programs – Examples from the Endocannabinoid System (IL05)

Isolation and Biological Activities of Natural Products and Analogues from the Adriatic Coral Eunicella Cavolini (OC02)

Lunch and Exhibition

Poster Session 1

Session Chair

New Catalytic Approaches for Simplifying Complex Amine Synthesis (IL06)

Challenges and Opportunities in CNS Drug Discovery (IL07)

Design and Optimization of High Performance KSPi ADCs With Increased Tumor Selectivity: Enhancing the Therapeutic Window by Legumain-Mediated ADC Activation (OC03)

Coffee-break and Exhibition

Enabling Technologies to Drive the MSD Portfolio (IL08)

Empowering Organic Synthesis: From Unique Methods to Complex Natural Products (IL09)

Closing of the day

Session Chair

Making Difficult-to-Make Molecules: Photochemistry as an Enabling Tool (IL25)

Structure Based Identification of Novel Albumin Binders for Half-Life Extensions of Proteins and Peptides (IL11)

High-Throughput Protac Synthesis and Direct to Biology Assaying for Rapidly Evaluating Targeted Protein Degradation (OC04)

Coffee-break and Exhibition

Phenotypic Screen to NLRP3 lead (IL12)

Genochemetic Diversification of Natural Products (IL13)

Development of Selective mTOR Inhibitors for the Treatment of Cancer and Neurological Disorders (OC05)

Lunch and Exhibition

Poster Session 2

Session Chair

Next Generation Design-Make-Test-Analysis-Cycles (IL14)

Making and Breaking of C-S Bonds Using Metal Catalysis (IL15)

Discovery of Imidazo[1,2-a]Pyridine Carboxamide BAY 1165747, a Long-Acting Soluble Guanylate Cyclase Stimulator for Resistant Hypertension (OC06)

Coffee-break and Exhibition

From BRD4 to KRAS: 12 Years of Oncology Small Molecules (IL16)

Synthesis of Glycosylated Natural Products or Analogues of Biological Interest (IL17)

Closing of the day

Session Chair

Machine Learning to Accelerate Design-Make-Test Cycles (IL18)

Covalent Chemical Biology with Natural Products and Novel Synthetic Warheads (IL19)

Direct Access to Unnatural Drug-Like Molecules by Photocatalytic Late-Stage Functionalization (OC07)

Coffee-break and Exhibition

Multicomponent Alkene Cross-Coupling by Base Metal Catalysis (IL20)

Novel, Reversible DCAF1 Ligands Expand the TPD-Toolbox (IL21)

Cocktails For 19F NMR Fragment Screening: From Theory to Applications Using Enamine’s Stock Chemical Space (OC08)

Lunch and Exhibition

Poster Session 3

Session Chair

Disrupting the YAP-TEAD Protein-Protein Interaction with Small Molecules - Discovery of Drug Candidate NVP-IAG933 (IL22)

EFMC Prizes Session - Ceremony & Lectures

EFMC Prize for a Young Medicinal Chemist or Chemical Biologist in Academia
Targeted Protein Degradation via Molecular Glues (PR01)

EFMC Prize for a Young Medicinal Chemist or Chemical Biologist in Industry
Discovery and Characterization of Potent, Efficacious and Orally Available Antimalarial Plasmepsin X Inhibitors (PR02)

EFMC-YMCS 2022 Best Oral Communication (OC09)
Epitope Identification Using In-Silico Approaches, a Case Study: Nanobodies Binding to MGlu5 Receptor

EFMC Best Practices Working Group

Coffee-break and Exhibition

First time disclosure
Discovery of the clinical candidate BI 1810631 (Zongertinib), a Selective HER2 Inhibitor for the Treatment of HER2 Exon 20 Insertion Driven Tumors (OC10)

Will Chemputers Dream of Electric Drugs (IL23)

Closing of the day

Symposium Banquet sponsored by Selvita

Session Chair

Taking Molecular Glue Degraders to New Heights (IL24)

The beautiful simplicity of rearrangements – towards ideal reactions? (IL10)
Chemistry Europe Speaker

RSC Medicinal Chemistry Lectureship
Time to Shine for Constrained Peptides in Medicinal Chemistry (OC11)

Coffee-break and Exhibition

Novel Modes of Enzyme Inhibition (IL26)

Natural Product Synthesis Through the Lens of Informatics (IL27)

Closing Remarks & Prize Ceremony

End of the symposium