IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry
Zagreb, Croatia September 3-7, 2023
Registration
Flow-enabled Synthesis of Fluorinated and Fluoroalkylated Moieties
MicroCycle: A Machine Learning Driven, Automated and Integrated Platform for Drug Discovery
OC01 - Divergent Synthesis as an Emergent Tool for Drug Discovery
Coffee-break and Exhibition
Synthesis of Fluorinated Molecules Using Modern Synthetic Tools
Chemical Probes and their Relevance for Drug Discovery Programs – Examples from the Endocannabinoid System
OC02 - Isolation and Biological Activities of Natural Products and Analogues from the Adriatic Coral Eunicella Cavolini
Lunch and Exhibition
New Catalytic Approaches for Simplifying Complex Amine Synthesis
Challenges and Opportunities in CNS Drug Discovery
OC03 - Design and Optimization of High Performance KSPi ADCs With Increased Tumor Selectivity: Enhancing the Therapeutic Window by Legumain-Mediated ADC Activation
Coffee-break and Exhibition
Enabling Technologies to Drive the MSD Portfolio
Novel Methods and Strategies for Rapid and Controlled Synthesis of Complex Antibiotics
Closing of the day
Can Chemistry Generate Biological Questions?
Structure Based Identification of Novel Albumin Binders for Half-Life Extensions of Proteins and Peptides
OC04 - High-Throughput Protac Synthesis and Direct to Biology Assaying for Rapidly Evaluating Targeted Protein Degradation
Coffee-break and Exhibition
Phenotypic Screen to NLRP3 lead
Precision Molecule Editing (a Game of Bio and Chemo-catalysis)
OC05 - Discovery of A Potent, Selective and Metabolically Stable mTOR Kinase Inhibitor Exploiting Morpholine Isosters
Lunch and Exhibition
Poster Session 1 (odd numbers)
Making and Breaking of C-S Bonds Using Metal Catalysis
OC06 - Discovery of Imidazo[1,2-a]Pyridine Carboxamide BAY 1165747, a Long-Acting Soluble Guanylate Cyclase Stimulator for Resistant Hypertension
Coffee-break and Exhibition
From BRD4 to KRAS: 12 Years of Oncology Small Molecules
Synthesis of Glycosylated Natural Products or Analogues of Biological Interest
Closing of the day
Machine Learning to Accelerate Design-Make-Test Cycles
Covalent Chemical Biology with Natural Products and Novel Synthetic Warheads
OC07 - Direct Access to Unnatural Drug-Like Molecules by Photocatalytic Late-Stage Functionalization
Coffee-break and Exhibition
Multicomponent Alkene Cross-Coupling by Base Metal Catalysis
Finerenone - A Novel Mineralo-Corticoid Receptor (MR) Antagonist
OC08 - Cocktails For 19F NMR Fragment Screening: From Theory to Applications Using Enamine’s Stock Chemical Space
Lunch and Exhibition
Poster Session 2 (even numbers)
Discovery of the First Orally Efficacious Small Molecules Disrupting the YAP-TEAD Interaction by Direct Competition
EFMC Prizes Session - Ceremony & Lectures
EFMC Prize for a Young Medicinal Chemist or Chemical Biologist in Academia
EFMC Prize for a Young Medicinal Chemist or Chemical Biologist in Industry
EFMC Prize Winner EFMC-YMCS 2022
Coffee-break and Exhibition
Why Chemputers Will Dream of Electric Drugs
Closing of the day
Symposium Banquet sponsored by Selvita
Taking Molecular Glue Degraders to New Heights
Making Difficult-to-Make Molecules: Photochemistry as an Enabling Tool
OC09
Coffee-break and Exhibition
Natural Product Synthesis Through the Lens of Informatics
Closing Remarks & Prize Ceremony
End of the symposium